GPR143 is a research area focused on the G protein-coupled receptor 143, a protein that is involved in the regulation of pigmentation in organisms. This receptor is particularly important in melanocytes, the cells responsible for producing the pigment melanin. Understanding the function and regulation of GPR143 can provide insights into various skin conditions, such as albinism and other pigmentation disorders. Research in this area may also have implications for the development of therapies for these conditions.