Glioblastoma is a type of aggressive and malignant brain tumor that arises from supporting cells in the brain called astrocytes. It is the most common and deadliest form of primary brain cancer in adults, with a very poor prognosis and limited treatment options. Glioblastoma is characterized by its rapid growth rate, infiltrative nature, and resistance to standard treatments such as surgery, radiation therapy, and chemotherapy. This tumor can cause a wide range of symptoms, depending on its location in the brain, including headaches, seizures, cognitive impairment, and neurological deficits. Research on glioblastoma focuses on understanding the underlying biology of the tumor, identifying potential therapeutic targets, and developing new treatment strategies to improve patient outcomes. Some of the promising areas of research include targeted therapies, immunotherapy, and precision medicine approaches tailored to the individual genetic profile of the tumor. Overall, glioblastoma remains a challenging disease to treat, and there is a great need for continued research efforts to find more effective treatment options and ultimately improve the prognosis for patients with this aggressive form of brain cancer.