18F-fluciclovine is a radiotracer used in positron emission tomography (PET) imaging to detect and localize recurrent prostate cancer in patients with elevated levels of prostate-specific antigen (PSA) after primary treatment. It is an amino acid analog that is taken up by prostate cancer cells due to their increased amino acid transport activity. 18F-fluciclovine PET imaging has shown promising results in accurately detecting recurrent prostate cancer, particularly in cases where conventional imaging methods such as CT scans or bone scans have been inconclusive. It is considered a valuable tool for guiding treatment decisions and monitoring response to therapy in prostate cancer patients.