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Courses
- MBMolecular Biophysics
- CBCell Biology
- TMTheoretical Mechanics
- CPComputational Physics
- AMAnalytical Mechanics
- HIOTHonors Introductory Optics and Thermodynamics
- ETElectromagnetic Theory
- CMContinuum Mechanics
- IMIntroductory Mechanics
- TSGCThe Science of Good Cooking
- HIRQPHonors Introductory Relativity and Quantum Physics
Grants
- Collaborative Research: Mapping Protein-membrane Interactions from Molecules to Cell-level Dynamics
Principal Investigator (PI)
2022
$383.8K
Active - Johns Hopkins Physical Sciences Oncology Center
Principal Investigator (PI)
2016
$119.7K
- Mechanochemistry of Bacterial Cell Wall Growth
Principal Investigator (PI)
2014
$392.2K
- The Dynamics of Contracting Gels During Cell Crawling and Blebbing
Principal Investigator (PI)
2013
$74.3K
- The Collective Dynamics of Cells in Tissues
Principal Investigator (PI)
2013
$25.3K
- Biophysics of the Morphology and Motility of Borrelia Burdorferi in Diverse Environment
Principal Investigator (PI)
2012
$587.5K
- Center for Cancer Physics
Principal Investigator (PI)
2012
$89.2K
News
- Mathematical Model Developed by UA Physicists Could Help Treat Lyme Disease
2014
Publications (80)
Recent
- A finite volume algorithm for the dynamics of filaments, rods, and beams
2022
- Taking the Monte‐Carlo gamble: How not to buckle under the pressure!
2022
- Twirling, whirling, and overwhirling revisited: Viscous dynamics of rotating filaments and ribbons
2022
- A general computational framework for the dynamics of single- and multi-phase vesicles and membranes
2021
- EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in developing neurons
2021
- The Axes of Life: A Roadmap for Understanding Dynamic Multiscale Systems
2021
- Sixth-Order Accurate Schemes for Reinitialization and Extrapolation in the Level Set Framework
2020
- Active random forces can drive differential cellular positioning and enhance motor-driven transport
2020
- Biophysics at the coffee shop: Lessons learned working with George Oster
2019
- Swimming bacteria power microspin cycles
2018
- Measuring DNA content in live cells by fluorescence microscopy
2018
- Vancomycin Reduces Cell Wall Stiffness and Slows Swim Speed of the Lyme Disease Bacterium
2017
- A minimal actomyosin-based model predicts the dynamics of filopodia on neuronal dendrites
2017
- Cellular Contraction Can Drive Rapid Epithelial Flows
2017
- New Continuum Approaches for Determining Protein-Induced Membrane Deformations
2017
- The induction of endoreduplication and polyploidy by elevated expression of 14-3-3γ
2017
- Going with the Flow: Water Flux and Cell Shape during Cytokinesis
2017
- On the Quantification of Cellular Velocity Fields
2016
- An immersed boundary method for two-phase fluids and gels and the swimming of Caenorhabditis elegans through viscoelastic fluids
2016
- Physical Mechanisms of Cancer in the Transition to Metastasis
2016
- Flagellar motility of the pathogenic spirochetes
2015
- Causes of retrograde flow in fish keratocytes
2014
- Spatiotemporal evolution of erythema migrans, the hallmark rash of lyme disease
2014
- Junctional angle of a bihanded helix
2014
- Force and torque on a cylinder rotating in a narrow gap at low Reynolds number: Scaling and lubrication analyses
2013
- Viscous dynamics of lyme disease and syphilis spirochetes reveal flagellar torque and drag
2013
- Elasticity and biochemistry of growth relate replication rate to cell length and cross-link density in rod-shaped bacteria
2013
- Biomechanics of cell motility
2012
- The unique paradigm of spirochete motility and chemotaxis
2012
- Surface traction and the dynamics of elastic rods at low Reynolds number
2012
- Swimming dynamics of the lyme disease spirochete
2012
- The heterogeneous motility of the Lyme disease spirochete in gelatin mimics dissemination through tissue
2012
- Crawling cells can close wounds without purse strings or signaling
2011
- Redundant mechanisms for stable cell locomotion revealed by minimal models
2011
- Mechanosensing can result from adhesion molecule dynamics
2011
- Advent of complex flows in epithelial tissues
2011
- Forces and torques on rotating spirochete flagella
2011
- Two-dimensional patterns in bacterial veils arise from self-generated, three-dimensional fluid flows
2011
- Swimming microorganisms in complex media
2010
- Mechanical response and conformational amplification in α-Helical coiled coils
2010
- Cytoskeletal cross-linking and bundling in motor-independent contraction
2010
- Processivity of peptidoglycan synthesis provides a built-in mechanism for the robustness of straight-rod cell morphology
2010
- The moving boundary node method: A level set-based, finite volume algorithm with applications to cell motility
2010
- Plant Biomechanics: Using Shape to Steal Motion
2009
- Live imaging reveals a biphasic mode of dissemination of Borrelia burgdorferi within ticks
2009
- The elastic basis for the shape of Borrelia burgdorferi
2009
- The flat-ribbon configuration of the periplasmic flagella of Borrelia burgdorferi and its relationship to motility and morphology
2009
- Swimming speeds of filaments in nonlinearly viscoelastic fluids
2009
- Biochemical mechanisms for regulating protrusion by nematode major sperm protein
2009
- Kinematics of the swimming of spiroplasma
2009
- Collective swimming and the dynamics of bacterial turbulence
2008
- Depolymerization-driven flow in nematode spermatozoa relates crawling speed to size and shape
2008
- Erratum: Elasticity of α-Helical coiled coils (Physical Review Letters (2006) 97 (248101))
2008
- Electron cryotomography reveals novel structures of a recently cultured termite gut spirochete
2008
- Genetic analysis of spirochete flagellin proteins and their involvement in motility, filament assembly, and flagellar morphology
2008
- Beating patterns of filaments in viscoelastic fluids
2008
- Z-ring force and cell shape during division in rod-like bacteria
2007
- Theory of swimming filaments in viscoelastic media
2007
- The shape and dynamics of the Leptospiraceae
2007
- pH and the crawling of nematode sperm
2006
- The flagellar cytoskeleton of the spirochetes
2006
- Erratum: Lamellipodial contractions during crawling and spreading (Biophysical Journal (2005) 89, (1643-1649))
2006
- Elasticity of α-helical coiled coils
2006
- MSP dynamics and retraction in nematode sperm
2005
- The kinky propulsion of Spiroplasma
2005
- Pattern formation by bacteria-driven flow
2005
- MSP dynamics drives nematode sperm locomotion
2005
- Force and flexibility of flailing myxobacteria
2005
- Bacterial swimming and oxygen transport near contact lines
2005
- Lamellipodial contractions during crawling and spreading
2005
- How to make a spiral bacterium
2005
- The junctional pore complex and the propulsion of bacterial cells
2004
- Dynamic supercoiling bifurcations of growing elastic filaments
2004
- The hydration dynamics of polyelectrolyte gels with applications to cell motility and drug delivery
2004
- Measurement of normal and anomalous diffusion of dyes within protein structures fabricated via multiphoton excited cross-linking
2004
- The motility of mollicutes
2003
- How myxobacteria glide
2002
- Bistable Helices
2000
- Chiral Self-Propulsion of Growing Bacterial Macrofibers on a Solid Surface
2000
- Twirling and whirling: Viscous dynamics of rotating elastic filaments
2000