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Profile
Tian Wang
Manager, Research - UAHS Brain Science | Assistant Research Professor, Neurology
Health Sciences Brain Science
Overview
Research
More
Collaboration
(5)
Francesca Vitali
Mutual work: 2 Proposals﹒1 Grant﹒1 Publication
Collaboration Details
Fei Yin
Mutual work: 5 Techs﹒2 Grants﹒1 Publication﹒3 Proposals
Collaboration Details
Roberta Brinton
Mutual work: 5 Techs﹒2 Grants﹒3 Publications﹒3 Proposals﹒1 Supervisor
Collaboration Details
Elsa Reyes Reyes
Mutual work: 2 Proposals﹒1 Grant
Collaboration Details
Kathleen Rodgers
Mutual work: 2 Proposals﹒1 Grant
Collaboration Details
Grants
(2)
Perimenopause in Brain Aging and Alzheimer's Disease
Active
·
2021
·
$2.1M / $11.1M
·
External
Co-Investigator (COI)
menopause,
brain aging,
alzheimer's disease
Aging and Estrogenic Control of the Bioenergetic System in Brain
Active
·
2017
·
$286.8K / $1.1M
·
External
Co-Investigator (COI)
aging,
estrogenic control,
bioenergetic system,
brain,
hormone regulation
Publications
(26)
Recent
Allopregnanolone pleiotropic action in neurons and astrocytes: calcium signaling as a unifying mechanism
2023
neuroscience,
astrocytes,
calcium signaling,
hormones,
neuropharmacology
Loss of fatty acid degradation by astrocytic mitochondria triggers neuroinflammation and neurodegeneration
2023
neuroinflammation,
neurodegeneration,
fatty acid degradation,
astrocytic mitochondria,
loss
Late gene therapy limits the restoration of retinal function in a mouse model of retinitis pigmentosa
2023
gene therapy,
retinal function,
retinitis pigmentosa,
mouse model,
restoration
A tale of two systems: Lessons learned from female mid-life aging with implications for Alzheimer s prevention treatment.
2022
aging,
alzheimer's,
mid-life,
female,
prevention
Translational potential of JAX humanized‐APOE mice model: Accelerated midlife endocrine aging in hAPOE epsilon;4/4 females
2022
translational research,
endocrine aging,
mice model,
apoe epsilon;4/4,
accelerated aging
Allopregnanolone potentiates bioenergetic capacity and mitochondrial biogenesis in astrocytes
2021
allopregnanolone,
bioenergetic capacity,
mitochondrial biogenesis,
astrocytes,
potentiation
A tale of two systems: Lessons learned from female mid-life aging with implications for Alzheimer's prevention treatment
2021
aging,
alzheimer's,
female health,
mid-life,
treatment
Von Willebrand factor A domain-containing protein 8 VWA8) localizes to the matrix side of the inner mitochondrial membrane
2020
mitochondrial function,
protein localization,
von willebrand factor,
cell biology,
bioinformatics
Evidence in support of chromosomal sex influencing plasma based metabolome vs APOE genotype influencing brain metabolome profile in humanized APOE male and female mice
2020
chromosomal sex,
metabolome profile,
apoe genotype,
humanized mice,
plasma-based metabolome
Allopregnanolone Promotes Neuronal and Oligodendrocyte Differentiation In Vitro and In Vivo: Therapeutic Implication for Alzheimer’s Disease
2020
alzheimer's disease,
neuronal differentiation,
oligodendrocyte differentiation,
therapeutic implication,
allopregnanolone