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Picture of George Sutphin

George Sutphin

Assistant Professor, Innovations in Aging - GIDP | Assistant Professor, Molecular and Cellular Biology | Assistant Professor, BIO5 Institute | Assistant Professor | Member of the Graduate Faculty | Assistant Professor, Cancer Biology - GIDP | Assistant Professor, Genetics - GIDP

Molecular and Cellular Biology

Collaboration(12)

Megha Padi
Kristian Doyle
Yana Zavros
Baldassarre Stea
Andrew Paek

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Grants(6)

Infection and Inflammation as Drivers of Aging (IIDA) Predoctoral Training Program
Active·2024·$0 / $292.3K·
External
Key Personnel (KP)
aging, infection, inflammation, pre-doctoral, training
An Automated High-Content Imaging Platform for Caenorhabditis Elegans
Active·2023·$675.7K / $900.9K·
External
Principal Investigator (PI)
high-content imaging, automated platform, caenorhabditis elegans, imaging, automation
Defining the Genetic Architecture of Multi-Stress Response
Active·2019·$2.1M·
External
Principal Investigator (PI)
genetic, stress response, multi-stress, genetic architecture, response
Glenn Foundation for Medical Research and AFAR Grant for Junior Faculty
Active·2019·$98.5K·
External
Principal Investigator (PI)
aging research, medical research, grant funding, junior faculty support, healthcare innovation
Targeting De Novo NAD+ Synthesis Through the Kynurenine Pathway in Renal Cell Carcinoma
2021·$150.3K·
External
Principal Investigator (PI)
cancer, metabolism, renal cell carcinoma, nad+ synthesis, kynurenine pathway

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Publications(83)

Recent

RAB27A knockout extends lifein C. elegans but not mice

2023

aging, genetics, model organisms, cell biology, species comparison

Standardized protocols for applying chemical stressors in Caenorhabditis elegans

2023

toxicology, genetics, ecotoxicology, experimental methods, animal models

Cadmium sensitizes Caenorhabditis elegans to osmotic stress by inhibiting glycerol production

2023

cadmium toxicity, osmotic stress response, glycerol metabolism, c. elegans physiology, heavy metal impact

3-hydroxyanthranilic acid promotes immune system resilience in aging Caenorhabditis elegans

2023

immunology, aging, resilience, metabolism, model organism

Global Rab27a null mutation alters the vascular microenvironment proteome and regulates vasoreactivity in mice

2023

genetic mutation, vascular biology, proteomics, vasoreactivity, mice model

LightSaver—A tool for rapid fluorescence quantification in individual C. elegans

2023

fluorescence quantification, c. elegans, research tool development, fluorescence microscopy, bioimaging

SICKO: Systematic Imaging of Caenorhabditis Killing Organisms

2023

imaging, pathogen, microscopy, nematode, infection

Inhibition of haao-1 enhances oxidative stress response by activating hormetic redox signaling in C. elegans.

2023

oxidative stress, redox signaling, inhibition, hormetic response, c. elegans

Developmental and longevity consequences of GRASP55 knockout in C. elegans and mice

2023

developmental biology, genetics, cell biology, longevity, model organisms

Subtle changes in diet alter aging interventions in C. elegans

2023

aging, diet, interventions, c. elegans, changes