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Rebecca Mosher is an Associate Professor in the School of Plant Sciences at the University of Arizona. After completing a BS at the University of Arizona, she performed doctoral work in the Program in Genetics and Genomics at Duke University, where she studied transcriptional control of plant immune responses. During graduate work Dr. Mosher discovered the emerging field of epigenetics and decided to pursue postdoctoral work with Sir David Baulcombe, first at the Sainsbury Laboratory in Norwich, UK and later at the University of Cambridge. During her postdoc, Dr. Mosher investigated the production of small RNAs by RNA Polymerase IV and demonstrated that these tiny transcriptional regulators are highly abundant during seed development. In 2010 Dr. Mosher returned to the University of Arizona, where she started a research group focused on small RNA directed DNA Methylation. Dr. Mosher has been the recipient of several fellowships and awards, including the NSF Graduate Research Fellowship, the Marshall-Sherfield Fellowship, the NSF International Research Fellowship, and the Bart Cardon Early Career Teaching Award.Show Less
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Courses
- APGAnimal and Plant Genetics
- PGGPlant Genetics and Genomics
- PGPPlant Growth and Physiology
Grants
- Collaborative Research: RESEARCH PGR: The epigenomic selfing syndrome: revealing the impact of breeding system on epigenomes
Principal Investigator (PI)
2023
$473.5K
Active - STC: Center for Research On Programmable Plant Systems
Principal Investigator (PI)
2021
$961.8K
Active - Understanding Alleles Influencing Seed Production in Brassica Rapa
Principal Investigator (PI)
2021
$500.0K
Active - EAGER: Biochemical and Genetic Tools for Analysis of Paralogous Polymerase Subunits in Grasses
Principal Investigator (PI)
2019
$299.1K
Active - RESEARCH PGR: Deciphering the Link Between RNA Directed DNA Methylation and Reproduction in Brassicaceae
Principal Investigator (PI)
2016
$2.3M
- RESEARCH-PGR: Deciphering the Link Between RNA Directed DNA Methylation and Reproduction in Brassicaceae
Principal Investigator (PI)
2016
$19.5K
- Mechanism and Function of Argonaute 4 Subcellular Localization
Principal Investigator (PI)
2013
$705.0K
Technologies / Patents
News
- Researchers Develop Tools to Listen, Talk to Plants with $25M from NSF
2021
- Grants Support Junior Faculty, Community Outreach Projects
2011
Publications (52)
Recent
- span style= font-size:10pt; A novel /span span style= font-size:10pt; CLAVATA1 /span span style= font-size:10pt; mutation causes multilocularity in /span em span style= font-size:10pt; Brassica rapa /span /em span style= font-size:medium; /span
2023
- Focus on RNA biology
2023
- span style= font-size:10pt; Small RNA mediated DNA methylation during plant reproduction /span span style= font-size:medium; /span
2023
- Small RNA-mediated DNA methylation during plant reproduction
2023
- A novel CLAVATA1 mutation causes multilocularity in Brassica rapa
2022
- A null allele of the pol IV second subunit impacts stature and reproductive development in Oryza sativa
2022
- Expansion and contraction of small RNA and methylation machinery throughout plant evolution
2022
- Quality control and evaluation of plant epigenomics data
2022
- Mapping a mutation causing pale yellow petals in Brassica rapa
2022
- Embryo CHH hypermethylation is mediated by RdDM and is autonomously directed in Brassica rapa.
2021
- A Null Allele of the Pol IV Second Subunit is Viable in Oryza sativa
2021
- Ovule siRNAs methylate protein-coding genes in trans
2021
- Plant Polymerase IV sensitizes chromatin through histone modifications to preclude spread of silencing into protein-coding domains
2021
- Small RNAs on the move in male germ cells.
2021
- Embryo CHH hypermethylation is mediated by RdDM and is autonomously directed in Brassica rapa
2020
- RNA-directed DNA Methylation and sexual reproduction: expanding beyond the seed.
2020
- RNA-directed DNA Methylation and sexual reproduction: expanding beyond the seed
2019
- Maternal small RNAs mediate spatial-temporal regulation of gene expression, imprinting, and seed development in Arabidopsis
2019
- Abundant expression of maternal siRNAs is a conserved feature of seed development
2019
- Evidence for a unique DNA-dependent RNA polymerase in cereal crops
2018
- Maternal components of RNA-directed DNA methylation are required for seed development in Brassica rapa
2018
- Maternal RNA-directed DNA methylation is required for seed development in Brassica rapa
2017
- Arabidopsis LORELEI, a Maternally Expressed Imprinted Gene, Promotes Early Seed Development
2017
- CoGe LoadExp+: A web-based suite that integrates next-generation sequencing data analysis workflows and visualization
2017
- Identification and Evolutionary Characterization of ARGONAUTE-Binding Platforms
2017
- Insights into Land Plant Evolution Garnered from the Marchantia polymorpha Genome
2017
- Combatting the Impostor Syndrome in academic science – you probably are as smart as they think!
2017
- The Argonaute‐binding platform of NRPE1 evolves through modulation of intrinsically disordered repeats
2016
- Exploiting mobile RNA silencing for crop improvement
2015
- Ancient origin and recent innovations of RNA polymerase IV and V
2015
- RNA-directed DNA methylation: an epigenetic pathway of increasing complexity
2014
- An Interview with Rebecca Mosher (review article)
2014
- Interview with Rebecca A. Mosher
2014
- Pol IV-Dependent siRNA Production is Reduced in Brassica rapa
2013
- Pinpointing a puzzling polymerase
2012
- Comparative functional genomics of the fission yeasts
2011
- An atypical epigenetic mechanism affects uniparental expression of Pol IV-dependent sirnas
2011
- Pol IV-Dependent siRNAs in Plants
2011
- siRNAs and DNA methylation: seedy epigenetics
2010
- RNA silencing in plants: Flash report!
2010
- Maternal control of Pol IV‐dependent siRNAs in Arabidopsis endosperm
2010
- Uniparental expression of PolIV-dependent siRNAs in developing endosperm of Arabidopsis
2009
- Analysis of small RNA in fission yeast; centromeric siRNAs are potentially generated through a structured RNA
2009
- Multimegabase silencing in nucleolar dominance involves siRNA-directed DNA methylation and specific methylcytosine-binding proteins
2008
- PolIVb influences RNA-directed DNA methylation independently of its role in siRNA biogenesis
2008
- Bacterial pathogens encode suppressors of RNA-mediated silencing.
2008
- Small RNAs hit the big time: Meetings
2007
- Small RNAs hit the big time
2007
- A comprehensive structure-function analysis of Arabidopsis SNI1 defines essential regions and transcriptional repressor activity
2006
- Functional Analysis of SNI1, a Novel Negative Regulator of Disease Resistance in Arabidopsis Thaliana
2005
- Seed production in sideoats grama populations with different grazing histories.
2000
- Seed Production in Sideoats Grama Populations with Different Grazing Histories
2000