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Parker Antin is Professor of Cellular and Molecular Medicine in the College of Medicine, Associate Vice President for Research for the Division of Agriculture, Life and Veterinary Medicine, and Cooperative Extension, and Associate Dean for Research in the College of Agriculture and Life Sciences. In his positions of Associate Vice President and Associate Dean, he is responsible for developing and implementing the research vision for the Colleges of Agriculture and Life Sciences and the College of Veterinary Medicine, with total research expenditures of approximately $65M per year. His responsibilities include oversight of research strategy and portfolio investment, grants and contracts pre award services, research intensive faculty hires and retentions, research communication and marketing, research facilities, and research compliance services. In collaboration with Division and College leadership teams, he has shared responsibilities for philanthropy, budgets and information technology. Dr. Antin is a vertebrate developmental biologist whose research is concerned with the molecular mechanisms of embryonic development. His research has been supported by NIH, NSF, NASA, USDA, and the DOE, as well as several private foundations including the American Heart Association and the Muscular Dystrophy Association, He is the Principal Investigator of CyVerse, a $115M NSF funded cyberinfrastructure project whose mission is to design, deploy and expand a national cyberinfrastructure for life sciences research, and train scientists in its use (http://cyverse.org). With 65,000 users worldwide, CyVerse enables scientists to manage and store data and experiments, access high-performance computing, and share data and results with colleagues and the public. Dr. Antin is also active nationally in the areas of science policy and funding for science. He is a past President of the Federation of Societies for Experimental Biology (FASEB), an umbrella science policy and advocacy organization representing 32 scientific societies and 135,000 scientists. His continued work with FASEB, along with his duties as Associate Vice President and Associate Dean for Research, and CyVerse PI, brings him frequently to Washington, DC, where he advocates for support of science and science policy positions that enhance the scientific enterprise.

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Courses
  • DB
    Developmental Biology

Grants
  • Funding agency logo
    Aviport: A Resource for Avian Biology

    Principal Investigator (PI)

    2017

    $3.2M
    Active
  • Funding agency logo
    CyVerse Implementation in TUG

    Co-Investigator (COI)

    2019

    $79.4K
  • Funding agency logo
    Root Genetics in the Field to Promote Drought Adaptation and Carbon Sequestration

    Co-Investigator (COI)

    2017

    $636.2K
  • Funding agency logo
    EAGER: Data Integration to Enable Cancer Research

    Principal Investigator (PI)

    2017

    $296.2K
  • Funding agency logo
    The iPlant Collaborative: Cyberinfrastructure for the Life Sciences

    Principal Investigator (PI)

    2013

    $50.3M
  • Funding agency logo
    Weinstein Cardiovascular Development Conference

    Principal Investigator (PI)

    2013

    $20.6K
  • Funding agency logo
    Program Income for Grant Acct 3006990

    Principal Investigator (PI)

    2013

    $8.5K
  • Funding agency logo
    Editorship of the Journal Developmental Dynamics

    Principal Investigator (PI)

    2012

    $555.1K
  • Funding agency logo
    Geisha: A Chicken Embryo Gene Expression Resource

    Principal Investigator (PI)

    2010

    $3.6M
  • Funding agency logo
    Induction of Cardiovascular Cells from HESCS by Embryonic Cues

    Principal Investigator (PI)

    2010

    $29.3K
News
  • CyVerse Receives Third NSF Award for Enabling Data Science

    2018

  • NSF's iPlant Collaborative Rebrands to CyVerse

    2016

  • Building Research Infrastructure for the Infinite

    2016

  • Parker Antin: Leading Life Science Initiatives

    2015

  • Two UA Honors Students Named Goldwater Scholars

    2008

  • UA Researchers Host International Heart Development Conference

    2005

  • Sarver Heart Center Awarded $8.8 Million NIH Grant to Study Heart Development

    2000

  • NIH Awards $8.8 Million Grant to UA Sarver Heart Center Researchers

    2000

Publications (86)
Recent
  • Birth of a pathway for sulfur metabolism in early amniote evolution

    2020

  • Definitions and Guidelines for Research on Epithelial-Mesenchymal Transition

    2020

  • Two Proximally Close Priority Candidate Genes for diplopodia-1, an Autosomal Inherited Craniofacial-Limb Syndrome in the Chicken: MRE11 and GPR83

    2019

  • Transitions

    2017

  • A conversation with rudolf jaenisch

    2016

  • Gastrulation EMT Is Independent of P-Cadherin Downregulation

    2016

  • Gastrulation EMT is Independent of Epithelial Cadherin Downregulation

    2016

  • Research data: Silver lining to irreproducibility

    2016

  • The iPlant Collaborative: Cyberinfrastructure for Enabling Data to Discovery for the Life Sciences

    2016

  • Third Report on Chicken Genes and Chromosomes 2015

    2015

  • LNA-based in situ hybridization detection of mRNAs in embryos

    2014

  • Embryonic expression of the transforming growth factor beta ligand and receptor genes in chicken

    2014

  • GEISHA: An evolving gene expression resource for the chicken embryo

    2014

  • A digital upgrade as 113 years of print publication comes to an end

    2013

  • The interesting times of science

    2013

  • Defining the Sequence Elements and Candidate Genes for the Coloboma Mutation

    2013

  • Olfactomedin-1 activity identifies a cell invasion checkpoint during epithelial-mesenchymal transition in the chick embryonic heart

    2013

  • Micro-RNA-195 and -451 regulate the LKB1/AMPK signaling axis by targeting MO25

    2012

  • Wnt signaling and a Smad pathway blockade direct the differentiation of human pluripotent stem cells to multipotent neural crest cells (Proceedings of the National Academy of Sciences (2011) 108, 48 (19240-19245) DOI: 10.1073/pnas.1113746108)

    2012

  • Fibroblast Growth Factor (FGF) signaling during gastrulation negatively modulates the abundance of microRNAs that regulate proteins required for cell migration and embryo patterning

    2012

  • FGF signalling through RAS/MAPK and PI3K pathways regulates cell movement and gene expression in the chicken primitive streak without affecting E-cadherin expression

    2011

  • Accelerated evolution of 3'avian FOXE1 genes, and thyroid and feather specific expression of chicken FoxE1

    2011

  • Wnt signaling and a Smad pathway blockade direct the differentiation of human pluripotent stem cells to multipotent neural crest cells

    2011

  • Whole mount in situ hybridization detection of mRNAs using short LNA containing DNA oligonucleotide probes

    2010

  • Arsenic exposure perturbs epithelial-mesenchymal cell transition and gene expression in a collagen gel assay

    2010

  • Leiomodin-2 is an antagonist of tropomodulin-1 at the pointed end of the thin filaments in cardiac muscle

    2010

  • Embryonic expression of the chicken Krüppel-like (KLF) transcription factor gene family

    2010

  • Network Elucidation Template: A framework for human-guided network inference

    2010

  • BioNetBuilder2.0: bringing systems biology to chicken and other model organisms

    2009

  • The Chicken Gene Nomenclature Committee report

    2009

  • One process for pancreatic β-cell coalescence into islets involves an epithelial-mesenchymal transition

    2009

  • In a world with many development journals, why choose to publish in developmental dynamics?

    2009

  • Myocardin expression during avian embryonic heart development requires the endoderm but is independent of BMP signaling

    2008

  • Non-canonical Wnt signaling through Wnt5a/b and a novel Wnt11 gene, Wnt11b, regulates cell migration during avian gastrulation

    2008

  • Open Access: AR is Fully Compliant with Mandates from NIH and Other Funding Agencies

    2008

  • DD is fully compliant (and then some) with NIH and other funding agencies

    2008

  • Gallus expression in situ hybridization analysis: a chicken embryo gene expression database

    2007

  • Erratum: MicroRNA expression during chick embryo development (Developmental Dynamics 235 (3156-3165))

    2007

  • GEISHA: An in situ hybridization gene expression resource for the chicken embryo

    2007

  • Differences in vertebrate microRNA expression

    2006

  • Has2 expression in heart forming regions is independent of BMP signaling

    2006

  • MicroRNA expression during chick embryo development

    2006

  • Depolymerized hyaluronan induces vascular endothelial growth factor, a negative regulator of developmental epithelial-to-mesenchymal transformation

    2006

  • Latrophilin-2 is a novel component of the epithelial-mesenchymal transition within the atrioventricular canal of the embryonic chicken heart

    2006

  • Hot hearts in the Sonoran Desert: the 11th Weinstein Cardiovascular Development Conference in Tucson

    2006

  • Genomic resources for chicken

    2005

  • Disruption in the tropomodulin1 (Tmod1) gene compromises cardiomyocyte development in murine embryonic stem cells by arresting myofibril maturation

    2005

  • A bigger bang for your buck: Enhanced access to your chick data

    2004

  • Regulation of Hex gene expression and initial stages of avian hepatogenesis by Bmp and Fgf signaling

    2004

  • GEISHA, a whole-mount in situ hybridization gene expression screen in chicken embryos

    2004

  • The Chick Embryo Rules (Still)!

    2004

  • Hedgehog signaling is essential for endothelial tube formation during vasculogenesis

    2004

  • The complete mouse nebulin gene sequence and the identification of cardiac nebulin

    2003

  • Tetracycline-inducible system for regulation of skeletal muscle-specific gene expression in transgenic mice

    2003

  • Ephs and ephrins during early stages of chick embryogenesis

    2003

  • Precocious expression of cardiac troponin T in early chick embryos is independent of bone morphogenetic protein signaling

    2002

  • Erratum: Precocious expression of cardiac troponin T in early chick embryos is independent of bone morphogenetic protein signaling (Developmental Dynamics)

    2002

  • Regulation of Hex gene expression by a Smads-dependent signaling pathway

    2002

  • Expression of the receptor tyrosine kinase gene EphB3 during early stages of chick embryo development

    2001

  • Assembly of thick, thin, and titin filaments in chick precardiac explants

    2001

  • To the heart of myofibril assembly

    2000

  • The RNA-binding protein gene, hermes, is expressed at high levels in the developing heart

    1999

  • Expression of the homeobox gene Hex during early stages of chick embryo development

    1999

  • The bovine calpastatin gene promoter and a new N-terminal region of the protein are targets for cAMP-dependent protein kinase activity

    1998

  • Regulation of avian cardiac myogenesis by activin/TGFβ and bone morphogenetic proteins

    1998

  • cAMP responsiveness of the bovine calpastatin gene promoter

    1998

  • Induction of cardiac myogenesis in avian pregastrula epiblast: The role of the hypoblast and activin

    1997

  • Cloning and sequencing of a developmentally regulated avian mRNA containing the LEA motif found in plant seed proteins

    1996

  • Regulation of avian precardiac mesoderm development by insulin and insulin-like growth factors

    1996

  • Expression of avian glypican is developmentally regulated

    1996

  • Expression of gap junction protein Cx43 in cultured human normal and malignant lung cells

    1994

  • Precardiac mesoderm is specified during gastrulation in quail

    1994

  • Transgene expression in the QM myogenic cell line

    1991

  • Isolation and characterization of an avian myogenic cell line

    1991

  • Single cell analysis of transfected gene expression in primary heart cultures containing multiple cell types

    1988

  • Analysis of the upstream regions governing expression of the chicken cardiac troponin T gene in embryonic cardiac and skeletal muscle cells

    1988

  • Effects of a phorbol ester (TPA) and a carcinogen (EMS) on myofibrillogenesis

    1986

  • Role of stress fiber-like structures in assembling nascent myofibrils in myosheets recovering from exposure to ethyl methanesulfonate

    1986

  • Myogenic lineages and myofibrillogenesis.

    1986

  • Interactions between IFs, microtubules, and myofibrils in fibrogenic and myogenic cells.

    1985

  • Induction of incoordinate synthesis of muscle proteins by the tumor promoter TPA and the carcinogen EMS.

    1985

  • The relationship between stress fiber-like structures and nascent myofibrils in cultured cardiac myocytes

    1984

  • Quantal and proliferative cell cycles: how lineages generate cell diversity and maintain fidelity.

    1983

  • Different proteins associated with 10-nanometer filaments in cultured chick neurons and nonneuronal cells

    1981

  • The effects of taxol on postmitotic myoblasts in culture

    1981

  • Taxol induces postmitotic myoblasts to assemble interdigitating microtubule-myosin arrays that exclude actin filaments

    1981

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