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Profile
Methajit Methawasin
Assistant Research Professor, Cellular and Molecular Medicine - (Research Series Track)
Cellular & Molecular Medicine
Full Page
Overview
Research
More
Collaboration
(6)
John Konhilas
Mutual work: 1 Grant﹒1 Proposal
Collaboration Details
Paul Langlais
Mutual work: 1 Grant﹒3 Proposals
Collaboration Details
Hendrikus Granzier
Mutual work: 5 Grants﹒9 Proposals﹒1 Publication
Collaboration Details
Jared Churko
Mutual work: 4 Proposals
Collaboration Details
Jil Tardiff
Mutual work: 2 Grants﹒4 Proposals
Collaboration Details
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Grants
(4)
Sex-specific Myofilament Dysfunction in Postmenopausal HFpEF
Active
·
2023
·
$403K / $447.8K
·
External
Principal Investigator (PI)
cardiovascular disease,
myocardial dysfunction,
gender differences,
postmenopausal health,
myofilament dysfunction
Posttranscriptional Regulation of RNA Binding Proteins in Heart Failure
Active
·
2020
·
$136.8K / $155.4K
·
External
Co-Investigator (COI)
rna binding proteins,
heart failure,
post-transcriptional regulation,
gene expression,
cardiovascular disease
Integrative Studies of Diastolic Function of Cardiomyocytes in Health and Disease
2019
·
$231K
·
External
Principal Investigator (PI)
cardiomyocyte function,
diastolic dysfunction,
integrative studies,
cardiac health,
disease mechanisms
Mechanical Triggers to Programmed Cell Death in Cardiomyocytes - and How to Prevent Their Action in Failing Hearts
2014
·
$0 / $1.1M
·
External
Co-Investigator (COI)
cell death,
cardiomyocytes,
mechanical triggers,
heart failure,
prevention
Publications
(27)
Recent
KBTBD13 is a novel cardiomyopathy gene
2022
cardiomyopathy,
genetics,
novel gene,
heart disease,
medical genetics
RBM20<sup>S639G<sup> mutation is a high genetic risk factor for premature death through RNA-protein condensates.
2022
genetic risk factors,
rna-protein condensates,
premature death,
mutation
Shortening the thick filament by partial deletion of titin's C-zone alters cardiac function by reducing the operating sarcomere length range
2022
cardiac function,
titin,
sarcomere length,
thick filament,
myocardial mechanics
Response by Methawasin and Granzier to Letter Regarding Article, Phosphodiesterase 9a Inhibition in Mouse Models of Diastolic Dysfunction"
2021
phosphodiesterase inhibition,
diastolic dysfunction,
mouse models,
letter response,
cardiovascular research
Phosphodiesterase 9a Inhibition in Mouse Models of Diastolic Dysfunction.
2020
cardiovascular,
phosphodiesterase,
mouse models,
diastolic dysfunction,
inhibition
Muscular changes in animal models of heart failure with preserved ejection fraction: what comes closest to the patient?
2020
heart failure,
animal models,
muscular changes,
ejection fraction,
patient relevance
Sarcomere length-dependent effects on Ca-troponin regulation in myocardium expressing compliant titin
2019
cardiac physiology,
titin biology,
muscle contraction,
calcium regulation,
sarcomere length
Deleting Full Length Titin Versus the Titin M-Band Region Leads to Differential Mechanosignaling and Cardiac Phenotypes.
2019
cardiac phenotypes,
mechanosignaling,
titin,
deletion,
m-band region
Osteopontin Promotes Left Ventricular Diastolic Dysfunction Through a Mitochondrial Pathway
2019
osteopontin,
left ventricular,
diastolic dysfunction,
mitochondrial pathway,
cardiac function
Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance
2019
metformin,
diastolic function,
hfpef,
titin compliance,
mouse model
