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Profile
Methajit Methawasin
Assistant Research Professor
Cellular & Molecular Medicine
Overview
Research
More
Collaboration
(5)
Jil Tardiff
Mutual work: 4 Proposals﹒2 Grants
Collaboration Details
Jared Churko
Mutual work: 3 Proposals
Collaboration Details
Paul Langlais
Mutual work: 3 Proposals﹒1 Grant
Collaboration Details
John Konhilas
Mutual work: 1 Proposal﹒1 Grant
Collaboration Details
Hendrikus Granzier
Mutual work: 5 Grants﹒1 Publication﹒9 Proposals
Collaboration Details
Grants
(4)
Posttranscriptional Regulation of RNA Binding Proteins in Heart Failure
Active
·
2020
·
$136.8K / $155.4K
·
External
Co-Investigator (COI)
rna binding proteins,
heart failure,
post-transcriptional regulation,
gene expression,
cardiovascular disease
Sex-specific Myofilament Dysfunction in Postmenopausal HFpEF
2023
·
$3.6M / $403.1K
·
External
Principal Investigator (PI)
cardiovascular disease,
myocardial dysfunction,
gender differences,
postmenopausal health,
myofilament dysfunction
Integrative Studies of Diastolic Function of Cardiomyocytes in Health and Disease
2019
·
$231K
·
External
Principal Investigator (PI)
cardiomyocyte function,
diastolic dysfunction,
integrative studies,
cardiac health,
disease mechanisms
Mechanical Triggers to Programmed Cell Death in Cardiomyocytes - and How to Prevent Their Action in Failing Hearts
2014
·
$0 / $1.1M
·
External
Co-Investigator (COI)
cell death,
cardiomyocytes,
mechanical triggers,
heart failure,
prevention
Publications
(36)
Recent
RBM20 mutation is a high genetic risk factor for premature death through RNA-protein condensates
2022
genetic risk factors,
rna-protein condensates,
premature death,
genetic research
KBTBD13 is a novel cardiomyopathy gene.
2022
cardiomyopathy,
gene,
novel,
kbtbd13,
cardiomyopathy gene
Shortening the thick filament by partial deletion of titin's C-zone alters cardiac function by reducing the operating sarcomere length range.
2022
cardiac function,
titin deletion,
sarcomere length,
thick filament,
contractile protein
Shortening the thick filament by partial deletion of titin's C-zone alters cardiac function by reducing the operating sarcomere length range
2022
cardiac function,
titin,
sarcomere length,
thick filament,
myocardial mechanics
Response by Methawasin and Granzier to Letter Regarding Article, Phosphodiesterase 9a Inhibition in Mouse Models of Diastolic Dysfunction
2021
phosphodiesterase inhibition,
diastolic dysfunction,
mouse models,
letter response,
cardiac research
Response by Methawasin and Granzier to Letter Regarding Article, Phosphodiesterase 9a Inhibition in Mouse Models of Diastolic Dysfunction"
2021
phosphodiesterase inhibition,
diastolic dysfunction,
mouse models,
letter response,
cardiovascular research
Phosphodiesterase 9a Inhibition in Mouse Models of Diastolic Dysfunction
2020
phosphodiesterase inhibition,
diastolic dysfunction,
mouse models,
cardiovascular research,
drug development
Muscular changes in animal models of heart failure with preserved ejection fraction: what comes closest to the patient?
2020
heart failure,
animal models,
muscular changes,
ejection fraction,
patient relevance
Metformin improves diastolic function in an HFpEF-like mouse model by increasing titin compliance
2019
metformin,
diastolic function,
hfpef,
titin compliance,
mouse model
Osteopontin Promotes Left Ventricular Diastolic Dysfunction Through a Mitochondrial Pathway
2019
osteopontin,
left ventricular,
diastolic dysfunction,
mitochondrial pathway,
cardiac function