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Courses
- CBCancer Basics
- ATCBAdvanced Topics in Cancer Biology
- SCScientific Communication
- CDCancer Discoveries
- CDBCell and Developmental Biology
- TBCThe Biology of Cancer
Grants
- Induction of Lysosomal Trafficking to Target Growth and Metastasis
Principal Investigator (PI)
2018
$556.6K
- STTR: Combinatorial Inactivation of ERBB Receptors In Breast Cancer using Therapeutic Stapled Peptides
Principal Investigator (PI)
2016
$149.1K
- Decoy Peptides: Development of a Novel Therapeutic for Metastatic Cancer
Principal Investigator (PI)
2013
$100.5K
- Theranostic Development for the Treatment of Metastatic Breast Cancer
Principal Investigator (PI)
2012
$112.1K
- Theranostic Development for the Treatment of Metastatic Breast Cancer
Principal Investigator (PI)
2011
$112.5K
- The Role of HUGL-1 in Epithelial Cell Polarity and Breast Cancer
Co-Investigator (COI)
2011
$98.9K
- MUC1 Expression Promotes erdb-B3 Dependent Signaling and Facilitates Cell Transformation
Co-Investigator (COI)
2011
$91.7K
- Theranostic Development for the Treatment of Metastatic Breast Cancer
Principal Investigator (PI)
2010
$112.5K
- Therapeutic Peptides for the Treatment of Metastatic Cancer
Principal Investigator (PI)
2010
$42.7K
- Mechanisms Underlying Cell Polarity in Breast Tumors
Co-Investigator (COI)
2009
$566.8K
Technologies / Patents
News
- UArizona Testing App to Alert Students, Employees Exposed to COVID-19
2020
- UArizona and Covid Watch Launch COVID-19 Exposure Notification App
2020
- New Molecular Research Discovery May Translate to New Treatments for Viral Diseases
2016
- UA Students Take Aim on Top Careers in STEM
2015
- Research Forum Acknowledges Undergraduate Scholarship
2008
- TRIF Funding at the UA: BIO5, Arizona Cancer Center Pursuing First-Class Cancer Therapies
2007
Publications (59)
Recent
- Sorting nexin-dependent therapeutic targeting of oncogenic epidermal growth factor receptor
2023
- Application of Microfluidic Systems for Breast Cancer Research
2022
- Cxcl10 Chemokine Induces Migration of ING4-Deficient Breast Cancer Cells via a Novel Cross Talk Mechanism between the Cxcr3 and Egfr Receptors
2022
- Wrong place at the wrong time: how retrograde trafficking drives cancer metastasis through receptor mislocalization
2019
- Stapled EGFR peptide reduces inflammatory breast cancer and inhibits additional HER-driven models of cancer
2019
- Wrong Place at the Wrong Time: How Retrograde Trafficking of Receptor Tyrosine Kinases Drives Cancer Metastasis
2018
- MiR-9a mediates the role of Lethal giant larvae as an epithelial growth inhibitor in Drosophila
2018
- mediates the role of Lethal giant larvae as an epithelial growth inhibitor in
2018
- Clinicopathological and Molecular Characteristics of Pleomorphic Invasive Lobular Carcinoma
2017
- Intravesicular epidermal growth factor receptor subject to retrograde trafficking drives epidermal growth factor-dependent migration
2017
- em miR-9a /em mediates the role of Lethal giant larvae as an epithelial growth inhibitor in em Drosophila /em
2017
- Opposing Regulation of the EGF Receptor: A Molecular Switch Controlling Cytomegalovirus Latency and Replication
2016
- Llgl1 prevents metaplastic survival driven by epidermal growth factor dependent migration
2016
- Isolation of viable cancer cells in antibody-functionalized microfluidic devices
2014
- Inactive ERBB receptors cooperate with reactive oxygen species to suppress cancer progression
2013
- MUC1 and metastatic cancer: Expression, function and therapeutic targeting
2013
- MUC1 drives c-Met-dependent migration and scattering
2012
- MUC1 Drives c-Met ndash;Dependent Migration and Scattering
2012
- On the minimum detection limit of circulating tumor cells in an antibody-functionalized microchannel array
2012
- Hugl1 and Hugl2 in mammary epithelial cells: polarity, proliferation, and differentiation
2012
- Flow-rate dependent capture of circulating tumor cells in bio-functional microchannels
2012
- Understanding the dual nature of CD44 in breast cancer progression
2011
- Adhesion dynamics of circulating tumor cells under shear flow in a bio-functionalized microchannel
2011
- Cell receptor and surface ligand density effects on dynamic states of adhering circulating tumor cells
2011
- A high-performance microsystem for isolating circulating tumor cells
2011
- Dynamic states of adhering cancer cells under shear flow in an antibody-functionalized microchannel
2011
- CD44 Promotes Epithelial Mammary Gland Development and Exhibits Altered Localization during Cancer Progression
2011
- Kinematics of specifically captured circulating tumor cells in bio-functionalized microchannels
2010
- MUC1 regulates nuclear localization and function of the epidermal growth factor receptor
2010
- Quantitative specific binding of breast cancer cells in an antibody-functionalized microchamber array
2010
- Specific binding of cancer cells using a microchamber array functionalized with antibodies
2010
- Matrix hyaluronan alters epidermal growth factor receptor-dependent cell morphology
2010
- Anti-cancer therapies that utilize cell penetrating peptides
2010
- Pilot study on the effects of dietary conjugated linoleic acid on tumorigenesis and gene expression in PyMT transgenic mice
2010
- Detachment of captured cancer cells under flow acceleration in a bio-functionalized microchannel
2009
- Flow acceleration effect on canser cell deformation abd detachment
2009
- Attachment & detachment of prostate cancer cells in a microfluidic system
2008
- Intracellular MUC1 Peptides Inhibit Cancer Progression
2008
- Go or Grow: How HA Controls the EGF Receptor
2008
- MUC1 is a novel regulator of ErbB1 receptor trafficking
2007
- Transforming growth factor α-dependent cancer progression is modulated by Muc1
2007
- Transforming growth factor alpha dependent cancer progression is modulated by Muc1
2007
- Transforming Growth Factor alpha; ndash;Dependent Cancer Progression Is Modulated by Muc1
2007
- CD44 Attenuates Metastatic Invasion during Breast Cancer Progression
2005
- MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation
2004
- MUC1 can interact with adenomatous polyposis coli in breast cancer
2004
- Form and function of developing heart valves: coordination by extracellular matrix and growth factor signaling
2003
- MUC1 alters β-catenin-dependent tumor formation and promotes cellular invasion
2003
- Heart-valve mesenchyme formation is dependent on hyaluronan-augmented activation of ErbB2-ErbB3 receptors
2002
- ErbB-β-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu transgenic carcinomas
2002
- Transgenic MUC1 Interacts with Epidermal Growth Factor Receptor and Correlates with Mitogen-activated Protein Kinase Activation in the Mouse Mammary Gland
2001
- Cooperative induction of mammary tumorigenesis by TGFα and Wnts
2000
- Dynamic expression and activation of ERBB receptors in the developing mouse mammary gland
1998
- Transgenic mice reveal roles for TGFα and EGF receptor in mammary gland development and neoplasia
1997
- Characterization of the mouse transforming growth factor gene: Its expression during eyelid development and in waved 1 tissues
1996
- Inhibition of Mammary Gland Involution Is Associated with Transforming Growth Factor α but not c-myc-induced Tumorigenesis in Transgenic Mice
1995
- Recognition Molecules and Immunoglobulin Domains in Invertebrates
1994
- Evaluation of Drosophila melanogaster as an alternative animal for studying the neurotoxicity of heavy metals
1992
- Isolation of a putative protoimmunoglobulin in Pyura hausteria
1991