KMap
Courses
- SMOSynthetic and Mechanistic Organic Chemistry
- MORMechanisms of Organic Reactions
- TCBTopics in Chemical Biology
- LOCLectures in Organic Chemistry
- HLOHonors Lectures in Organic Chemistry
Student Thesis/Dissertation
- Expanding the Chemical Probe Toolbox for Selective Bioconjugation and Targeted Delivery
2023
doctoral - Forging the Bioconjugate Toolbox: Development of Novel Probes for Orthogonal and Bioorthogonal Protein Functionalization
2022
doctoral - Base-Activated Lysine Probes and their Utility in Mosquito Larvae Midguts
2022
doctoral - SYNTHESIS OF NOVEL TRIAZINES, CHEMICAL PROPERTIES AND THEIR APPLICATIONS IN BIOCHEMISTRY
2022
bachelors - Protected Triazabutadienes in Chemical Biology
2021
doctoral - Synthetically Diverse Triazabutadienes and Their Applications Towards Biological Systems
2021
doctoral - The Development of Contrast Agents for PET/MRI and CatalyCEST MRI
2019
doctoral - Studies of the Reactivity of Selected Nitrogen-Rich Compounds
2019
doctoral - Design and Synthesis of Modular Reagents for Chemical Biology
2018
doctoral - Design and Synthesis of Triazabutadiene-based Fluorogenic Probes for Tyrosine Specific Labeling of Proteins
2018
doctoral - Detection of Enzyme Activity in a Pancreatic Tumor Model Using CatalyCEST Contrast MRI
2017
masters - Triazabutadienes and a Glycoprotein-Targeted Photocrosslinker as Protein-Labeling Agents
2017
doctoral - Using Bioorthogonal Chemistry for Investigating Dengue Virus Interactome
2017
bachelors - Development of Clickable Triazabutadienes as Cleavable Cross-Linkers
2016
masters - Triazabutadiene Chemistry in Organic Synthesis and Chemical Biology
2016
doctoral - Characterization of 4-demethylwyosine Synthase, a Radical S-adenosyl-l-methionine Enzyme Involved in the Modification of tRNA
2016
doctoral - A Bioorthogonal Approach to Chemical Virology
2016
doctoral
Grants
- Leveraging Releasable Aryl Diazonium Ions to Probe Biochemical Systems
Principal Investigator (PI)
2023
$450.8KActive - Research Collaboration Agreement
Principal Investigator (PI)
2022
$82.3KActive - James H. Gilliam, Jr. Fellowship for Advanced Study
Principal Investigator (PI)
2019
$150.0K - CAREER: Triazabutadienes as a Versatile Tool in Chemical Biology
Principal Investigator (PI)
2016
$640.1K - Fundamental understanding of the reaction to generate organic diazo compounds from azido-organic starting materials
Principal Investigator (PI)
2013
$100.0K
Technologies / Patents
News
- UA Doctoral Student, Adviser Earn Prestigious Gilliam Fellowship
2019
- Three UA Researchers Earn NSF CAREER Grants
2016
- Program Preps UA Inventions for Market
2016
- TLA Asset Demo Program Readies Inventions
2015
- Chemistry Program Promotes Discovery-Based Experiences
2013
Publications (28)
Recent
- Direct intracellular delivery of benzene diazonium ions as observed by increased tyrosine phosphorylation
2022
- Highly stable Meldrum’s acid derivatives for irreversible aqueous covalent modification of amines
2020
- Discriminating changes in protein structure using tyrosine conjugation
2020
- Determining protein structure by tyrosine bioconjugation
2020
- Coumarin triazabutadienes for fluorescent labeling of proteins
2018
- Synthesis of fluorescent heterocycles via a Knoevenagel/4+1]cycloaddition cascade using acetyl cyanide
2017
- Rapid in Situ Generation of Benzene Diazonium Ions under Basic Aqueous Conditions from Bench-Stable Triazabutadienes
2017
- Hexyl triazabutadiene as a potent alkylating agent
2017
- A gradient-free method for the purification of infective dengue virus for protein-level investigations
2016
- Cu-Click Compatible Triazabutadienes To Expand the Scope of Aryl Diazonium Ion Chemistry
2016
- Light-Activated Triazabutadienes for the Modification of a Viral Surface
2016
- Protecting triazabutadienes to afford acid resistance
2016
- Water‐Soluble Triazabutadienes that Release Diazonium Species upon Protonation under Physiologically Relevant Conditions
2015
- A photobasic functional group
2015
- A traceless staudinger reagent to deliver diazirines
2013
- d-Amino Acid Chemical Reporters Reveal Peptidoglycan Dynamics of an Intracellular Pathogen
2013
- Probing the Mycobacterial Trehalome with Bioorthogonal Chemistry
2012
- Reactivity of biarylazacyclooctynones in copper-free click chemistry
2012
- Synthesis of a fluorogenic cyclooctyne activated by Cu-free click chemistry
2011
- Inhibition of eukaryotic translation elongation by the antitumor natural product Mycalamide B
2011
- Temporary restraints to overcome steric obstacles: An efficient strategy for the synthesis of mycalamideB
2010
- Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones
2010
- Cu-free click cycloaddition reactions in chemical biology
2010
- Difluorobenzocyclooctyne: synthesis, reactivity, and stabilization by β-cyclodextrin
2010
- Preparation of S)4-Isopropyl-N-propanoyl-1,3-thiazolidine-2-thione
2009
- Total synthesis of pederin
2007
- Palladium-catalyzed asymmetric phosphination. Enantioselective synthesis of PAMP-BH sub 3 sub ligand effects on catalysis, and direct observation of the stereochemistry of transmetalation and reductive elimination
2003
- Palladium-Catalyzed Asymmetric Phosphination. Enantioselective Synthesis of PAMP−BH3, Ligand Effects on Catalysis, and Direct Observation of the …
2003
Please report any missing, incorrect data issues or provide feedback to help us improve the KMap.
Grants
Citations
H-Index
Patents
News
Books
Opportunities