Expanding the Chemical Probe Toolbox for Selective Bioconjugation and Targeted Delivery

Forging the Bioconjugate Toolbox: Development of Novel Probes for Orthogonal and Bioorthogonal Protein Functionalization

Base-Activated Lysine Probes and their Utility in Mosquito Larvae Midguts

SYNTHESIS OF NOVEL TRIAZINES, CHEMICAL PROPERTIES AND THEIR APPLICATIONS IN BIOCHEMISTRY

Protected Triazabutadienes in Chemical Biology

Synthetically Diverse Triazabutadienes and Their Applications Towards Biological Systems

The Development of Contrast Agents for PET/MRI and CatalyCEST MRI

Studies of the Reactivity of Selected Nitrogen-Rich Compounds

Design and Synthesis of Modular Reagents for Chemical Biology

Design and Synthesis of Triazabutadiene-based Fluorogenic Probes for Tyrosine Specific Labeling of Proteins

Detection of Enzyme Activity in a Pancreatic Tumor Model Using CatalyCEST Contrast MRI

Triazabutadienes and a Glycoprotein-Targeted Photocrosslinker as Protein-Labeling Agents

Using Bioorthogonal Chemistry for Investigating Dengue Virus Interactome

Development of Clickable Triazabutadienes as Cleavable Cross-Linkers

Triazabutadiene Chemistry in Organic Synthesis and Chemical Biology

Characterization of 4-demethylwyosine Synthase, a Radical S-adenosyl-l-methionine Enzyme Involved in the Modification of tRNA

UA Doctoral Student, Adviser Earn Prestigious Gilliam Fellowship

Three UA Researchers Earn NSF CAREER Grants

Program Preps UA Inventions for Market

TLA Asset Demo Program Readies Inventions

Direct intracellular delivery of benzene diazonium ions as observed by increased tyrosine phosphorylation

Highly stable Meldrum’s acid derivatives for irreversible aqueous covalent modification of amines

Discriminating changes in protein structure using tyrosine conjugation

Determining protein structure by tyrosine bioconjugation

Coumarin triazabutadienes for fluorescent labeling of proteins

Synthesis of fluorescent heterocycles via a Knoevenagel/4+1]cycloaddition cascade using acetyl cyanide

Rapid in Situ Generation of Benzene Diazonium Ions under Basic Aqueous Conditions from Bench-Stable Triazabutadienes

Hexyl triazabutadiene as a potent alkylating agent

A gradient-free method for the purification of infective dengue virus for protein-level investigations

Cu-Click Compatible Triazabutadienes To Expand the Scope of Aryl Diazonium Ion Chemistry

Light-Activated Triazabutadienes for the Modification of a Viral Surface

Protecting triazabutadienes to afford acid resistance

Water‐Soluble Triazabutadienes that Release Diazonium Species upon Protonation under Physiologically Relevant Conditions

A photobasic functional group

A traceless staudinger reagent to deliver diazirines

d-Amino Acid Chemical Reporters Reveal Peptidoglycan Dynamics of an Intracellular Pathogen

Probing the Mycobacterial Trehalome with Bioorthogonal Chemistry

Reactivity of biarylazacyclooctynones in copper-free click chemistry

Synthesis of a fluorogenic cyclooctyne activated by Cu-free click chemistry

Inhibition of eukaryotic translation elongation by the antitumor natural product Mycalamide B

Temporary restraints to overcome steric obstacles: An efficient strategy for the synthesis of mycalamideB

Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones

Cu-free click cycloaddition reactions in chemical biology

Difluorobenzocyclooctyne: synthesis, reactivity, and stabilization by β-cyclodextrin

Preparation of S)4-Isopropyl-N-propanoyl-1,3-thiazolidine-2-thione

Total synthesis of pederin

Palladium-catalyzed asymmetric phosphination. Enantioselective synthesis of PAMP-BH sub 3 sub ligand effects on catalysis, and direct observation of the stereochemistry of transmetalation and reductive elimination