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Dr. Watts is co-director of the University of Arizona Cancer Center (UACC) Genomics Shared Service supported by the UACC and the Southwest Environmental Health Sciences Center. He has 20 years of molecular biology experience with emphasis on analysis of nucleic acids including their isolation and quality control, sequencing, expression, and data analysis.Show Less
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Courses
- PACDPharmacology of Anti-Cancer Drugs
- CHPComprehensive Human Pharmacology
- IDPInfectious Disease Pharmacology
Grants
- I-Corps: Rapid Home Microbiome Diagnostics Tests
Co-Investigator (COI)
2020
$50.0K
Active - Southwest Environmental Health Sciences Center
Co-Investigator (COI)
2018
$7.3M
Active - Improving the Diagnosis of Febrile Neutropenia in Hematopoeitic Stem Cell Transplant Patients
Principal Investigator (PI)
2016
$74.9K
- Southwest Environmental Health Sciences Center
Co-Investigator (COI)
2012
$8.3M
- Arizona Cancer Center - Cancer Center Support Grant
Co-Investigator (COI)
2009
$27.1M
- Arizona Cancer Center - Cancer Center Support Grant (NON Supplement)
Co-Investigator (COI)
2009
$61.4K
- Southwest Environmental Health Sciences Center
Co-Investigator (COI)
2006
$7.8M
Technologies / Patents
News
- Researcher Uses 'Shotgun Sequencing' to Study Microorganisms
2018
- UA Employees Have Strong '40 Under 40' Showing
2009
- Campus Scientists to Explore Biomedical Research
2005
Publications (44)
Recent
- Liquid biopsy, using a novel DNA methylation signature, distinguishes pancreatic adenocarcinoma from benign pancreatic disease
2022
- An adaptable and non-invasive method for tracking Bifidobacterium animalis subspecies lactis 420 in the mouse gut
2021
- Metagenomic Next-Generation Sequencing in Clinical Microbiology
2020
- Speed, accuracy, sensitivity and quality control choices for detecting clinically relevant microbes in whole blood from patients
2019
- Paraneoplastic Leukemoid Reaction Associated with Increased Levels of and Tumor Overexpression of Receptors for G-CSF, GM-CSF, and IL-6: A Clinico-Pathological-Molecular Study
2018
- 16S rRNA gene sequencing on a benchtop sequencer: accuracy for identification of clinically important bacteria
2017
- Characterization of a novel radiation-induced sarcoma cell line.
2015
- Fn14 receptor promotes invasive potential and metastatic capacity of non-small lung adenocarcinoma cells through the up-regulation of integrin α6
2015
- Innovative qPCR using interfacial effects to enable low threshold cycle detection and inhibition relief
2015
- Abstract 1200: Characterization of a novel radiation-induced sarcoma cell line
2014
- Environmental arsenic exposure and microbiota in induced sputum
2014
- Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations
2014
- Three-dimensional printing surgical instruments: are we there yet?
2014
- Maintenance of mitochondrial genomic integrity in the absence of manganese superoxide dismutase in mouse liver hepatocytes
2013
- The matrix protein CCN1/CYR61 is required for α(V)β5-mediated cancer cell migration
2012
- Abstract 1641: Concordance between mutations identified by bar-coded multiplexed sequencing of BRAF, NRAS, and KIT in formalin fixed (FFPE) tissue from melanoma patients using the Ion Torrent Personal Genome Machine (PGM) and a real-time PCR assay
2012
- The decreased expression of Beclin-1 correlates with progression to esophageal adenocarcinoma: the role of deoxycholic acid
2012
- A novel mechanism of acid and bile acid-induced DNA damage involving Na+/H+ exchanger: implication for Barrett's oesophagus
2010
- S1626 A Novel Mechanism of Bile Acid Induced Damage: Relevance to Esophageal Carcinogenesis
2010
- Expression of bile acid transporting proteins in Barrett's esophagus and esophageal adenocarcinoma
2009
- Agglomerative epigenetic aberrations are a common event in human breast cancer
2008
- M1957 Expression of Bile Acid Transporting Proteins in Barrett s Esophagus and Esophageal Adenocarcinoma
2008
- DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage
2008
- Different mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells
2008
- Profiling of selenomethionine responsive genes in colon cancer by microarray analysis
2007
- Identification of Fn14/TWEAK receptor as a potential therapeutic target in esophageal adenocarcinoma
2007
- Large-scale regulatory network analysis from microarray data: modified Bayesian network learning and association rule mining
2007
- Pharmacogenomics of the polyamine analog 3,8,13,18-tetraaza-10,11-[(E)-1,2-cyclopropyl]eicosane tetrahydrochloride, CGC-11093, in the colon adenocarcinoma cell line HCT1161
2006
- AP-2alpha and AP-2gamma are transcriptional targets of p53 in human breast carcinoma cells
2006
- Epigenetic inactivation of the HOXA gene cluster in breast cancer
2006
- The chemopreventive agent alpha-difluoromethylornithine blocks Ki-ras-dependent tumor formation and specific gene expression in Caco-2 cells
2004
- The acetyltransferase p300/CBP-associated factor is a p53 target gene in breast tumor cells.
2004
- Performance evaluation of commercial short-oligonucleotide microarrays and the impact of noise in making cross-platform correlations
2004
- Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression
2003
- Low-level arsenite induced gene expression in HEK293 cells
2003
- Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate
2002
- Laminin-5-mediated gene expression in human prostate carcinoma cells
2001
- Microarray analysis of a human multiple myeloma cell line selected with melphalan or doxorubicin identifies a set of commonly affected genes
2001
- Glioma cell motility is associated with reduced transcription of proapoptotic and proliferation genes: a cDNA microarray analysis.
2001
- cDNA microarray analysis of multidrug resistance: doxorubicin selection produces multiple defects in apoptosis signaling pathways
2001
- Implementing microarrays for the study of plant genomics
1999
- Gene expression profiles associated with MDR1 expression in a doxorubicin-resistant human multiple myeloma cell line
1999
- Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene
1997
- Detecting differences in 5-methylcytosine using restriction enzyme isoschizomers: an endogenous control for complete digestion
1995