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Profile
Vijay Gokhale
Member of the Graduate Faculty | Associate Research Professor
BIO5 Institute
Overview
Research
More
Collaboration
(27)
Todd Vanderah
Mutual work: 3 Proposals﹒1 Tech﹒1 Publication
Collaboration Details
Elsa Reyes Reyes
Mutual work: 2 Techs
Collaboration Details
Stefano Guerra
Mutual work: 2 Proposals
Collaboration Details
Dean Billheimer
Mutual work: 1 Proposal
Collaboration Details
Denise Roe
Mutual work: 2 Proposals
Collaboration Details
Page 1 of 6
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Grants
(9)
Cytoskeletal Regulation of Lung Endothelial Pathobiology in ARDS
Active
·
2022
·
$53.5K / $2.1M
·
External
Co-Investigator (COI)
cytoskeletal regulation,
lung endothelial,
ards,
pathobiology,
research
DYRK1A Inhibition as a Novel Treatment Approach for Alzheimer's Disease
Active
·
2020
·
$151.7K / $3M
·
External
Co-Investigator (COI)
alzheimer's,
dyrk1a,
inhibition,
treatment,
novel
Small Molecules Targeting TDP-43 - RNA Interactions in ALS
2018
·
$210.9K / $702.9K
·
External
Co-Investigator (COI)
als,
small molecules,
tdp-43,
rna interactions,
neurodegeneration
Preclinical Development of Small-Molecule Inhibitors Targeting Nox4 for Pulmonary Fibrosis
2017
·
$869.3K / $4.3M
·
External
Co-Investigator (COI)
pulmonary fibrosis,
small molecule inhibitors,
nox4,
preclinical development,
research
Regulators of NaV1.7 Channels: Novel Anti-Allodynic Drug Candidates
2017
·
$33.7K
·
External
Principal Investigator (PI)
ion channels,
pain management,
drug discovery,
neuroscience,
pharmacology
Page 1 of 2
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Publications
(74)
Recent
Quindoline-derivatives display potent G-quadruplex-mediated antiviral activity against herpes simplex virus 1.
2022
antiviral,
g-quadruplex,
herpes simplex virus 1,
quindoline-derivatives,
drug development
Selective targeting of NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents
2021
pain,
neuroscience,
drug development,
rodents,
protein-protein interaction
Targeting of the Long Noncoding RNA MALAT1
2021
rna,
gene expression,
cancer,
molecular biology,
gene regulation
Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex
2020
gene regulation,
transcription,
nucleolin,
g-quadruplex,
androgen receptor
An Allosteric Modulator of RNA Binding Targeting the N-Terminal Domain of TDP-43 Yields Neuroprotective Properties
2020
rna binding,
neuroprotective,
allosteric modulation,
tdp-43,
n-terminal domain
Erratum: Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex
2020
In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells
2019
cancer,
drug discovery,
leukemia,
g-quadruplex,
cell death
Abstract 5226: Non-canonical functions of TERT in glioblastoma pathobiology
2019
tert functions,
glioblastoma,
non-canonical,
pathobiology,
functions
CBMT-23. NON-CANONICAL FUNCTIONS OF TERT IN GLIOBLASTOMA
2019
tert,
glioblastoma,
non-canonical functions,
cancer,
genetics
Abstract 2967: Activity of G-quadruplex stabilizing small molecule that downregulates MYC and synergizes with Navitoclax in acute myeloid leukemia cells
2019
g-quadruplex,
myc regulation,
small molecules,
acute myeloid leukemia,
drug synergy