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Lingling An, PhD, is an adjunct Associate Professor of Biostatistics at the University of Arizona Mel and Enid Zuckerman College of Public Health. Dr. An received her PhD in Statistics from Purdue University and joined the UA in 2008 as Assistant Professor of Biometry in Department of Ag & Biosystems Engineering.
Dr. An has extensive experience in collaborative research and methodological research in the areas of Statistical Bioinformatics, Genomics/Metagenomics, and Pattern recognition. Specifically, her research focuses on developing novel statistical methods and efficient computational algorithms to better utilize various types of massive data generated by high throughput biological technologies (e.g., next generation sequencing) to ask, answer, and disseminate biomedically interesting information in the quest to systematically understand the complex diseases, including cancer, aging, diabetes, and asthma. Show Less
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Courses
- DEDesign of Experiments
- SSSurvey Sampling
- SBGAStatistical Bioinformatics and Genomic Analysis
- ABApplied Biostatistics
- CBComputation in Biomedicine
Grants
- Assessment of Speech Sound Disorders in Latino Preschoolers: An Evidence Based Procedure.
Key Personnel (KP)
2022
$173.7K
Active - Binational Early Asthma & Microbiome Study (BEAMS)
Co-Investigator (COI)
2020
$9.1M
Active - The Positive Roles of Lysine Deacetylase Complexes in Regulating Transcriptional Dynamics
Key Personnel (KP)
2020
$1.1M
- Misdiagnosis of Speech Sound Disorders in Latino Children
Co-Investigator (COI)
2015
$412.2K
- ATD: Statistical Methods for Functional Metagenomics in Biothreat Detection
Principal Investigator (PI)
2012
$723.0K
- ATD: A Mixture Modeling Framework for Statistical Identification of Multiple Genomes in Metagenomics Samples
Principal Investigator (PI)
2010
$95.1K
Publications (49)
Recent
- Nrf2 signaling in heart failure: expression of Nrf2, Keap1, antioxidant, and detoxification genes in dilated or ischemic cardiomyopathy
2022
- table tr td /td /tr /table table tr td p style= font-size:11px; Attention-based Graph Neural Network for Label Transfer in Single Cell Multiomics Data span /span /p /td /tr /table
2022
- Editorial: Methods for Single-Cell and Microbiome Sequencing Data
2022
- NISC: Neural Network-Imputation for Single-Cell RNA Sequencing and Cell Type Clustering
2022
- A Distribution-Free Model for Longitudinal Metagenomic Count Data
2022
- Comparison and impact of COVID-19 for patients with cancer: a survival analysis of fatality rate controlling for age, sex and cancer type
2021
- Loss of Endothelial Hypoxia Inducible Factor-Prolyl Hydroxylase 2 Induces Cardiac Hypertrophy and Fibrosis
2021
- Phonological Measures for Bilingual Spanish-English Speaking Preschoolers: The Language Combination Effect
2021
- N-Acetylcysteine for Cardiac Protection during Coronary Artery Reperfusion: A Comprehensive Systematic Review and Meta-Analysis of Twenty Eight Randomized Controlled Trials
2021
- Ensemble dimensionality reduction and feature gene extraction for single-cell RNA-seq data
2020
- Normalization methods on single-cell RNA-seq data: an empirical survey
2020
- An Information-based Approach for Mediation Analysis on High-dimensional Metagenomic Data
2020
- On fusion methods for knowledge discovery from multi-omics datasets
2020
- Microbial community dissimilarity for source tracking with application in forensic studies
2020
- Mie scattering and microparticle-based characterization of heavy metal ions and classification by statistical inference methods
2019
- scDoc: Correcting Drop-out Events in Single-cell RNA-seq Data
2019
- FERTILIZATION-INDEPENDENT SEED-Polycomb Repressive Complex 2 plays a dual role in regulating type I MADS-box genes in early endosperm development
2018
- The Club Cell Marker SCGB1A Downstream of FOXA1 is Reduced in Asthma
2018
- Evaluation of season, cultivar, and aeration on biomass production of greenhouse hydroponic lettuce
2017
- An Informative Approach on Differential Abundance Analysis for Time-course Metagenomic Sequencing Count Data
2017
- A CFD study on improving air flow uniformity in indoor plant factory system
2016
- Model Selection and Estimation with Quantal-Response Data in Benchmark Risk Assessment
2016
- Classification, predictive modelling, and statistical analysis of cancer data.
2015
- A robust approach for identifying differentially abundant features in metagenomic samples
2015
- An on-line CNV detection method for short sequencing reads
2015
- A COMPUTATIONAL FLUID DYNAMICS MODEL OF ALGAL GROWTH: DEVELOPMENT AND VALIDATION
2015
- Investigating microbial co-occurrence patterns based on metagenomic compositional data
2015
- Accurate Genome Relative Abundance Estimation for Closely Related Species in a Metagenomic Sample
2014
- Classification, predictive modelling, and statistical analysis of cancer data
2014
- A Statistical approach for profiling functionality of a microbial community
2014
- A statistical approach to correcting cross-annotations in a metagenomic functional profile
2014
- A two-stage statistical procedure for feature selection and comparison in functional analysis of metagenomes
2014
- Accurate Estimation of Genome Relative Abundance for Closely Related Species in a Metagenomic Sample
2014
- Statistical approach of functional profiling for a microbial community
2014
- Analysis of microclimate uniformity in a naturally vented greenhouse with a high-pressure fogging system
2013
- Class I lysine deacetylases facilitate glucocorticoid-induced transcription.
2013
- nformation-theoretic model-averaged benchmark dose analysis in environmental risk assessment
2013
- The impact of model uncertainty on benchmark dose estimation
2012
- Dynamic Clustering of Gene Expression
2012
- A Statistical Framework for Accurate Taxonomic Assignment of Metagenomic Sequencing Reads
2012
- Modeling Drug-Carrier Interaction in the Drug Release from Nanocarriers
2011
- Comparative functional genomic analysis of Solanum glandular trichome types
2011
- Detection of rare functional variants using group ISIS
2011
- The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy
2010
- Visualizing desirable patient healthcare experiences
2010
- Gene expression analysis at the intersection of ploidy and hybridity in maize
2009
- Presynaptic calcium channel localization and calcium-dependent synaptic vesicle exocytosis regulated by the fuseless protein
2008
- DAG Lipase Activity Is Necessary for TRP Channel Regulation in Drosophila Photoreceptors
2008
- Analysis of gene expression profiles in response to Sclerotinia sclerotiorum in Brassica napus
2007