PROJECT SUMMARY To expand the kidney-related biomedical workforce and counter the increasing disparity between the growingprevalence of renal disease and the disproportionate level of trainees researchers and practitioners innephrology and kidney health we developed the Arizona Technology Development and Clinical EducationProgram for Students in Kidney Health (ADVANCE Kidney Health). ADVANCE Kidney Health is an education-based hands-on research education and clinical experience that applies pillars of 1) science medical andengineering education; 2) training in innovation entrepreneurialism and scientific translation; 3) experientiallearning mentorship and clinical immersion; and 4) needs-based application and practical translation all aimedat producing motivated trained and committed biomedical trainees interested in renal health and science toadvance the workforce and develop the new health-related therapies of the future. The program recruitsundergraduate students from across 15 departments within the College of Engineering at the University ofArizona (UArizona) that include: Biomedical Engineering Electrical and Computer Engineering MechanicalEngineering and Chemical Engineering. ADVANCE Kidney Health is structured to provide trainees a medicalschool experience for early-stage undergraduate learners geared to instill an understanding of renal anatomyand kidney function. The core structure accesses a clinical experience to instill a motivation to pursue kidney-related patient care and/or translational research and progresses to an already established innovation bootcampthat culminates in an interdisciplinary capstone that has doubled in size over 10 years and accesses by morethan 450 captive engineering students. The program leverages new infrastructure in medical and engineeringeducation along with transdisciplinary programs aimed at innovation technology development andentrepreneurialism with 15 physician navigators in kidney health and 23 engineering and scientific mentorsspanning renal physiology biomedical engineering optical sciences and machine learning. The result is aninterrelated program that bridges renal medicine engineering and product development to develop new pipelinesand on-ramps to impact career decisions and grow the future kidney-related workforce.