ARIZONA PRIDE-25: TRANSLATIONAL APPROACHES TO HEALTH DISPARITIES IN THE LUNGDespite significant advances in the understanding prevention detection and treatment of myriad healthconditions significant differences in prevalence rates health outcomes access and quality of care arepervasive in individuals from racial and ethnic minorities and other underserved communities. These healthand healthcare disparities represent a major challenge to achieving a healthy nation status. The ArizonaPRIDE-25 Translational Approaches to Health Disparities in the Lung will enhance diversity and capacity forhealth disparities solution-focused research among early career health science academics who come fromunder-represented backgrounds including minority groups and persons living with disabilities. We propose ayear-long program designed to support junior faculty and transitioning postdoctoral fellows by offering: inter-professional mentoring and career/leadership development activities; funded research project-basedexperience; grantsmanship and scientific writing training; and an individualized didactic curriculum thatintegrates research methodology and analysis for translational sciences applications to the solution of healthdisparities in lung conditions. The program offers participation in two summer sessions linked by a year-longeffort that integrates team mentoring research development and implementation experience and distancelearning inter-professional team-science career development and education program. The summer sessionswill include introduction to aspects of lung related health disparities research coupled with garneringexperience didactic training and skill building through direct involvement with diverse funded researchers whoare leaders in lung health disparities within the University of Arizona Health Sciences (UAHS) and externalpartners. Through a combination of onsite training and online delivery modalities mentees will receive formalinstruction in advanced biostatistics including health economics and big data analysis from molecular EHRand population health sources all tailored to the individual's need and research content. UAHS faculty willintroduce AZ-PRIDE mentees to grantsmanship bioethics scientific writing presentation workshops andspecial topics such as global border and Native American health. Issues relevant to career development andleadership training will be tailored to address specific needs of individuals from backgrounds traditionallyunderrepresented in biomedical research (UBR). AZ-PRIDE program will continue to expand its impact as anationwide facilitator of academic opportunities and development for early career UBR investigators. The resultwill be sustained reductions in health disparities through impactful basic behavioral clinical and socialsciences research and an impactful increase in the proportion of successful next generation UBR researchleaders.