Herpes simplex virus (HSV) is a common viral infection that causes sores or blisters, usually on the mouth (oral herpes) or genitals (genital herpes). There are two types of HSV: HSV-1, which typically causes oral herpes, and HSV-2, which typically causes genital herpes. HSV infections are usually mild, but can be recurrent and cause discomfort or embarrassment for those affected. Research in the area of herpes simplex virus focuses on understanding the virus's structure, replication cycle, and pathogenesis, as well as developing treatments and vaccines to prevent or control infections. Scientists are also investigating the mechanisms by which the virus establishes latency in nerve cells and reactivates to cause recurrent infections. Additionally, researchers are exploring novel antiviral therapies and exploring the impact of HSV infection on the immune system and overall health. Overall, research on herpes simplex virus aims to improve diagnosis, prevention, and treatment of HSV infections.