Coronary disease, also known as coronary artery disease or coronary heart disease, is a condition in which plaque builds up in the arteries that supply blood to the heart. This can lead to narrowed or blocked arteries, reducing blood flow to the heart muscle and increasing the risk of heart attacks and other cardiovascular events. Risk factors for coronary disease include high blood pressure, high cholesterol, smoking, obesity, diabetes, and a sedentary lifestyle. Researchers in this area study the causes, risk factors, prevention, and treatment of coronary disease, with the goal of improving outcomes and reducing the burden of this common and serious health condition. This research may include epidemiological studies, clinical trials, and basic science investigations into the mechanisms underlying the disease.