Chronic rhinosinusitis is a condition characterized by inflammation of the nasal passages and sinuses lasting for an extended period of time, typically over 12 weeks. Symptoms may include difficulty breathing through the nose, nasal congestion, facial pain or pressure, and reduced sense of taste or smell. The exact cause of chronic rhinosinusitis is not always clear, but it is thought to be related to a combination of factors such as allergies, infections, and structural problems in the nasal passages. Treatment may involve medications, nasal sprays, antibiotics, or surgery in severe cases. Research in this area focuses on understanding the underlying mechanisms of the condition, improving diagnostic techniques, and developing more effective treatments.