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Profile
Qing-Yu Zhang
Member of the Graduate Faculty | Professor, Pharmacology and Toxicology
Pharmacology and Toxicology
Full Page
Overview
Research
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Collaboration
(29)
Jefferey Burgess
Mutual work: 1 Grant﹒2 Proposals
Collaboration Details
Teshia Solomon
Mutual work: 1 Proposal﹒1 Grant
Collaboration Details
Nathan Cherrington
Mutual work: 5 Proposals﹒1 Grant
Collaboration Details
Wei Wang
Mutual work: 1 Grant﹒6 Proposals
Collaboration Details
Kelly Reynolds
Mutual work: 2 Proposals
Collaboration Details
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Grants
(18)
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Publications
(49)
Recent
JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both In Vitro and In Vivo.
2020
pharmacokinetics,
niclosamide,
zika virus,
antiviral,
drug development
Hepatic and intestinal biotransformation gene expression and drug disposition in a dextran sulfate sodium-induced colitis mouse model
2020
drug metabolism,
inflammatory bowel disease,
gene expression,
mouse model,
drug disposition
Proximal Tubular Vacuolization and Hypersensitivity to Drug-Induced Nephrotoxicity in Male Mice With Decreased Expression of the NADPH-Cytochrome P450 Reductase
2020
nephrotoxicity,
drug metabolism,
mouse models,
cytochrome p450,
renal tubular injury
Generation and characterization of a serum albumin‐humanized mouse model for biomarker discovery
2020
biomarker discovery,
mouse model,
serum albumin,
characterization,
generation
Contribution of Pulmonary CYP-mediated Bioactivation of Naphthalene to Airway Epithelial Injury in the Lung.
2020
pulmonary toxicity,
cyp enzymes,
naphthalene exposure,
airway epithelial injury,
lung bioactivation
Toxicokinetic Interaction between Hepatic Disposition and Pulmonary Bioactivation of Inhaled Naphthalene Studied Using Null and CYP2A13/2F1-Humanized Mice with Deficient Hepatic Cytochrome P450 Activity
2019
toxicokinetics,
inhalation exposure,
hepatic metabolism,
pulmonary bioactivation,
cytochrome p450
Role of mouse cytochrome P450 enzymes of the CYP2ABFGS subfamilies in the induction of lung inflammation by cigarette smoke exposure
2019
cytochrome p450 enzymes,
lung inflammation,
cyp2abfgs subfamilies,
cigarette smoke exposure,
mouse
Generation and characterization of a myeloid cell-specific Cyp19a1 knockout mouse model
2019
genetic engineering,
immunology,
animal model,
endocrinology,
cell biology
Regulation of Fgf15 expression in the intestine by glucocorticoid receptor
2019
gene expression,
hormone regulation,
intestinal biology,
glucocorticoid receptor,
regulatory mechanism
Contributions of Hepatic and Intestinal Metabolism to the Disposition of Niclosamide, a Repurposed Drug with Poor Bioavailability
2019
drug metabolism,
bioavailability,
drug repurposing,
hepatic metabolism,
intestinal metabolism
