VOSviewer
Grants
- The novel therapeutic targets to prevent right ventricle failure in pulmonary arterial hypertension
Key Personnel (KP)
2023
$231.0K
Active - Cytoskeletal Regulation of Lung Endothelial Pathobiology in ARDS
Co-Investigator (COI)
2022
$2.1M
Active - Anaplerotic Reprogramming of Endothelial Cells in Pulmonary Hypertension
Principal Investigator (PI)
2022
$1.3M
Active - Mitochondrial Dysfunction in Pulmonary Hypertension
Co-Investigator (COI)
2022
$673.7K
Active - Profiling Circulating Metabolites for the Diagnosis of Pulmonary Hypertension
Co-Investigator (COI)
2022
$129.5K
Active - The Role of Glucose-6-Phosphate Dehydrogenase Deficiency in Pulmonary Arterial Hypertension
Key Personnel (KP)
2021
$140.8K
Active - The Novel Role of Aminopeptidase-N in Pulmonary Hypertension
Key Personnel (KP)
2021
$136.8K
Active - Enabling the Early Diagnosis of Chronic Lung Diseases with a Blood-based Metabolomics Diagnostic Powered by Machine Learning
Principal Investigator (PI)
2021
$100.0K
Active - Hemolysis and Free Heme Signaling in Pulmonary Hypertension
Principal Investigator (PI)
2020
$1.6M
Active - Fatty Acid-binding Proteins Sustain Endothelial Glycolysis and Arterial Programming in Pulmonary Arterial Hypertension
Co-Investigator (COI)
2023
$575.8K
Technologies / Patents
News
- UArizona researchers develop AI-driven method for diagnosing lung disease
2022
- UArizona Startups Recognized at IdeaFunding 2021 Competition
2021
- UArizona reports record number of inventions
Publications (48)
Recent
- Cytokine profiling in pulmonary arterial hypertension: the role of redox homeostasis and sex
2022
- eNAMPT neutralization reduces preclinical ARDS severity via rectified NFkB and Akt/mTORC2 signaling
2022
- Single Mutation in the NFU1 Gene Metabolically Reprograms Pulmonary Artery Smooth Muscle Cells
2021
- Cytokine Profiling in Pulmonary Arterial Hypertension: the Role of Redox Homeostasis and Gender
2021
- Endothelial eNAMPT drives EndMT and preclinical PH: rescue by an eNAMPT-neutralizing mAb
2021
- Redox-dependent loss of flavin by mitochondria complex I is different in brain and heart
2021
- Glucose-6-phosphate dehydrogenase deficiency contributes to metabolic abnormality and pulmonary hypertension
2021
- Inhibition of Anaplerosis Attenuated Vascular Proliferation in Pulmonary Arterial Hypertension
2020
- Early progression of pulmonary hypertension in the monocrotaline model in males is associated with increased lung permeability
2020
- Single Mutation in the Gene Metabolically Reprograms Pulmonary Artery Smooth Muscle Cells
2020
- Necrosis-Released HMGB1 (High Mobility Group Box 1) in the Progressive Pulmonary Arterial Hypertension Associated With Male Sex
2020
- Antioxidant-Conjugated Peptide Attenuated Metabolic Reprogramming in Pulmonary Hypertension
2020
- Complex III Inhibition-Induced Pulmonary Hypertension Affects the Mitochondrial Proteomic Landscape
2020
- Heme induces rapid endothelial barrier dysfunction via the MKK3/p38MAPK axis
2020
- Pulmonary Arterial Hypertension Induces a Distinct Signature of Circulating Metabolites
2020
- Sex-specific stress response and HMGB1 release in pulmonary endothelial cells
2019
- Role of impaired reticulocyte maturation in pathogensis of pulmonary arterial hypertension
2019
- Mechanisms of right ventricle dysfunction in pulmonary hypertension induced by NFU1 insufficiency
2019
- Precision medicine approach in patients with pulmonary arterial hypertension: The importance of talking sex and redox profile in consideration
2019
- Bif-1 Interacts with Prohibitin-2 to Regulate Mitochondrial Inner Membrane during Cell Stress and Apoptosis
2019
- INOSITOL MONOPHOSPHATASE 1 (IMPA1) AS A NOVEL INTERACTING PARTNER OF RAGE IN PULMONARY HYPERTENSION
2019
- Pulmonary hypertension induced by severe mitochondrial dysfunction associated with altered glucose tolerance and insulin resistance
2019
- Role of Gender in Regulation of Redox Homeostasis in Pulmonary Arterial Hypertension
2019
- Inhibition of respiratory chain Complex III irreversibly changes the mitochondria proteomic landscape
2019
- Antioxidant conjugated peptide attenuated metabolic reprogramming in pulmonary hypertension
2019
- Gender Difference in Damage-Mediated Signaling Contributes to Pulmonary Arterial Hypertension
2019
- Rats with Human Mutation of NFU1 Develop Pulmonary Hypertension
2019
- Focus on Early Events: Pathogenesis of Pulmonary Arterial Hypertension Development
2019
- New cases of Glucose-6-Phosphate Dehydrogenase deficiency in Pulmonary Arterial Hypertension
2018
- Recurrent inhibition of mitochondrial complex III induces chronic pulmonary vasoconstriction and glycolytic switch in the rat lung
2018
- Hemolysis-induced Lung Vascular Leakage Contributes to the Development of Pulmonary Hypertension
2018
- LPS Induced Acute Lung Injury Involves the NF-κB-mediated Downregulation of SOX18
2017
- Hyper-activation of pp60(Src) limits nitric oxide signaling by increasing asymmetric dimethylarginine levels during acute lung injury
2017
- Molecular mechanisms of bio-catalysis of heme extraction from hemoglobin
2017
- Pulmonary arterial hypertension: are we close to the success?
2017
- Characterization of the CLASP2 Protein Interaction Network Identifies SOGA1 as a Microtubule-Associated Protein
2017
- Associations of Prolonged QTc in Sickle Cell Disease
2016
- RhoA S-nitrosylation as a regulatory mechanism influencing endothelial barrier function in response to G(+)-bacterial toxins
2016
- Redox regulation of epidermal growth factor receptor signaling during the development of pulmonary hypertension
2016
- Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed Rat Lung
2016
- Overexpression of Nitric Oxide Synthase Restores Circulating Angiogenic Cell Function in Patients With Coronary Artery Disease: Implications for Autologous Cell Therapy for Myocardial Infarction
2016
- Asymmetric Dimethylarginine Stimulates Akt1 Phosphorylation via Heat Shock Protein 70-Facilitated Carboxyl-Terminal Modulator Protein Degradation in Pulmonary Arterial Endothelial Cells
2016
- Activation of Calpain-2 by Mediators in Pulmonary Vascular Remodeling of Pulmonary Arterial Hypertension
2015
- Complex I dysfunction underlies the glycolytic switch in pulmonary hypertensive smooth muscle cells
2015
- Endothelial nitric oxide synthase deficient mice are protected from lipopolysaccharide induced acute lung injury
2015
- Nitric oxide induces hypoxia ischemic injury in the neonatal brain via the disruption of neuronal iron metabolism
2015
- Nitroalkenes confer acute cardioprotection via adenine nucleotide translocase 1
2015
- The sexual dimorphism associated with pulmonary hypertension corresponds to a fibrotic phenotype
2015